Why is the Think Again Think NP-C campaign important?

Currently Niemann-Pick type C disease (NP-C) takes, on average, five years to diagnose.1 However, NP-C is treatable and so this means that patients live for five years without treatment or access to support. Think Again. Think NP-C is a campaign led by the International Niemann-Pick Disease Alliance (INPDA), an alliance of non-profit Niemann-Pick disease patient support organisations across the world.

The campaign aims to reduce the time to diagnosis by supporting healthcare professionals who are unfamiliar with NP-C to recognise the key signs and symptoms of the disease. This will help patients by speeding up diagnosis so patients can access treatment and support.2


  1. Mengel E, Klünemann H, Lourenço C, et al. Niemann-Pick disease type C symptomatology: an expert-based clinical description. Orphanet J Rare Dis 2013; 8:166.
  2. Patterson M, Hendriksz, Walterfang M, et al. on behalf of the NP-C Guidelines Working Group. Recommendations for the diagnosis and management of Niemann-Pick disease type C: an update. Mol Genet Metab 2012; 106(3):330-44.


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